Strasbourg came from behind to beat Crystal Palace 2-1 at the Stade de la Meinau as the Eagles' hopes of finishing in the UEFA Conference League's top-eight positions were dented.
Jean-Philippe Mateta was the architect of the opening goal as the giant France striker initially did well to control a long ball, before holding off his markers on the edge of the box and then finding Tyrick Mitchell with a cheeky through-ball.
The left-back still had a lot of work to do from a tight angle, however his low drive nestled in the far corner and just seconds later the visitors came close to doubling their lead after Strasbourg's on-loan Chelsea goalkeeper Mike Penders went walkabout.
Ismaila Sarr could only hit the inside of the post from 30 yards and Palace were made to pay for that open-goal miss when Strasbourg hit back eight minutes into the second half after a brilliantly worked team goal that ended with the impressive Emanuel Emegha - who joins Chelsea next season - converting at the back post.
The Eagles then spurned two great chances to re-take the lead as first substitute Adam Wharton hit the bar with the goal gaping after a mix-up at the back by the hosts, before Penders denied Yeremy Pino.
Oliver Glasner's side were made to pay when Strasbourg went in front for the first time 13 minutes from time when ex-Brighton forward Julio Enciso's delightful free kick hit the crossbar, with 19-year-old Moroccan Samir El Mourabet reacting quickest to turn home the rebound.
As a result, Palace's recent five-game unbeaten run in all competitions came to an end as they slipped down to 18th in the Conference League standings.