League One Mansfield Town will host Premier League leaders Arsenal, while Manchester City face a tricky-looking trip to Newcastle United in the fifth round of the FA Cup.
Mansfield's reward for knocking out Premier League outfit Burnley on Saturday, to seal a place in the fifth round for the first time in 50 years, was a glamour tie with Arsenal at the One Call Stadium.
Man City, who have won the famous old trophy on seven occasions - the last of which was three years ago - will need to repeat their Carabao Cup semi-final success over Newcastle if Pep Guardiola's side are to stay on track for a possible eighth triumph and make up for their shock loss to Crystal Palace in last season's final at Wembley.
Elsewhere, if non-league side Macclesfield Town - who stunned Palace in the third round - can cause another huge upset by getting the better of high-flying Premier League side Brentford on Monday evening, they will face more top-flight opposition in struggling West Ham United at the London Stadium.
Having booked their place in the fifth round for the first time in 29 years by beating Ipswich Town on Saturday, Wrexham have been handed a dream clash with eight-time winners Chelsea at the Racecourse Ground, while 2022 winners Liverpool - into the fifth round for just the fourth time in the last 11 seasons, visit relegation-threatened Wolverhampton Wanderers.
Completing the fifth-round lineup, Fulham host Southampton, Port Vale or Bristol City - who play their rearranged fourth-round tie on March 3 - entertain Sunderland, and Leeds United take on Norwich City at Elland Road as Daniel Farke comes up against his old club.
FA Cup fifth-round draw in full:
Ties to take place March 6-9
Key dates for the FA Cup 2025/26
Fifth round: Saturday March 7 2026
Quarter-finals: Saturday April 4 2026
Semi-finals: Saturday April 25 2026
Final: Saturday May 16 2026