The 24-year-old failed to impress in his first season at Old Trafford, scoring just three Premier League goals in 32 appearances.
Ruben Amorim has since splashed over £200 million on new forwards, and Zirkzee has fallen well down the pecking order at Old Trafford.
According to journalist John Cross, Serie A side Roma are ready to offer the Dutchman a way out and bring him back to Italy.
It’s understood that ‘there is no doubt he wants to leave’ United with his eyes on a place in the Netherlands’ World Cup squad next summer.
Relegation threated West Ham are also interested in Zirkzee as they fight to retain their Premier League status.